Tirzepatide dosage chart

The schedule in milligrams, then the same schedule in units — because if you're on compounded vials, milligrams aren't what you draw.

The schedule

Standard titration for tirzepatide (Zepbound, Mounjaro). Each step is held four weeks before the next.
When	Dose	What it's for
Weeks 1–4	2.5 mg	Starting dose. Tolerance only — not meant to be where you stay.
Weeks 5–8	5 mg	First dose intended to do the work. Many people stop here.
Weeks 9–12	7.5 mg	Only if 5 mg has stopped being enough.
Weeks 13–16	10 mg	A common landing place.
Weeks 17–20	12.5 mg
Week 21+	15 mg	Maximum. There is no 17.5.

Two things this chart won't tell you and a lot of pages imply. You don't have to reach the end. The ladder exists so the dose can keep rising if it needs to, not because 15 mg is the destination — plenty of people hold at 5 or 10 indefinitely. And the four weeks is a floor, not a target. Moving up faster is what turns tolerable nausea into a bad fortnight. Your prescriber sets the pace.

The same schedule, in units

Compounded tirzepatide is sold at a handful of concentrations. Find your vial's mg/mL on the label, then read down that column.

Units to draw on a U-100 insulin syringe. Red means it won't fit in one 100-unit syringe.
Dose	5 mg/mL	10 mg/mL	20 mg/mL	40 mg/mL
2.5 mg	50	25	12.5	6.25
5 mg	100	50	25	12.5
7.5 mg	150 ✗	75	37.5	18.75
10 mg	200 ✗	100	50	25
12.5 mg	250 ✗	125 ✗	62.5	31.25
15 mg	300 ✗	150 ✗	75	37.5

Read the red column ends before you order. At 5 mg/mL you run out of barrel after 5 mg. At 10 mg/mL you run out after 10 mg. If you're titrating upward and your pharmacy keeps sending 10 mg/mL, you will eventually be told to do two injections for one dose — or you'll need a more concentrated vial. Worth asking about at the step before you hit it.

One dose at a time

Each dose on its own page, at every strength, with the syringe drawn: 2.5 mg · 5 mg · 7.5 mg · 10 mg · 12.5 mg · 15 mg.

One vial at a time

Your vial's whole ladder, each step drawn on the barrel: 5 mg/mL · 10 mg/mL · 20 mg/mL · 40 mg/mL. Doses below 2.5 mg are on the microdosing page. Going the other way — you drew a number of units and want the milligrams — units to mg.

Your vial

If yours isn't one of those four concentrations, or the pharmacy sent powder for you to mix yourself:

Tirzepatide vial → unitsU-100 syringe

Vial strength mg

Water you added mL

Your dose mg

Syringe

—

Fill in all three boxes.

Common setups:

Vials and pens are different problems

	Branded pen	Compounded vial
What you set	Nothing. One pen, one dose, one click.	A volume, in units, that you work out.
Changing dose	A different pen arrives.	Same vial, you draw further up the barrel.
Doses available	2.5 / 5 / 7.5 / 10 / 12.5 / 15 only.	Anything, including in-between doses if your prescriber wants one.
What goes wrong	Very little.	Arithmetic, and U-40 syringes.

That flexibility is the reason some prescribers use vials for people who don't tolerate a full step up — a 6 mg or an 8.75 mg dose is impossible with pens and trivial with a vial. It's also the reason the conversion has to be right.

Doses that aren't on the ladder

Because it comes up: at 20 mg/mL, the in-between doses land like this.

Dose	Units at 20 mg/mL	Why anyone uses it
3.75 mg	18.75	Half-step when 5 mg was too much too soon.
6.25 mg	31.25	Same idea, one rung higher.
8.75 mg	43.75	Holding pattern below 10 mg.
11.25 mg	56.25	Rare. Usually a tolerance issue at 12.5.

These are not on any manufacturer's label. They exist because vials make them possible, and they only make sense if a prescriber put you there deliberately.

Related: the semaglutide chart, which has the same problem with a different set of numbers · what tirzepatide actually costs, including why the price you were quoted goes up as you titrate.